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ML382
Artikelnummer: TGM-T8538-100mg
Description: ML382 is a potent and selective MrgX1 positive allosteric modulator (EC50 : 190 nM). Target: MRGPR. Smiles: CCOc1ccccc1NC(=O)c1ccccc1NS(=O)(=O)C1CC1. References: Li Z, et al. Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain. Proc Natl Acad Sci U S A....
| Anwendung: | MRGPRX1 positive allosteric modulator |
| CAS | 1646499-97-9 |
| MW: | 360.43 D |
ab 39,00 €
ML-382
Artikelnummer: Cay36668-10
ML-382 is a positive allosteric modulator of MAS-related G protein-coupled receptor family member X1 (MRGPRX1). It potentiates activation of MRGPRX1 induced by the MRGPRX1 agonist BAM 22P (8-22) (Cay-35263) in HEK293 cells expressing the human receptor (EC50 = 0.19 µM) but does not potentiate activation of MRGPRX2...
| Schlagworte: | VU0485891, 2-[(cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)-benzamide |
| Anwendung: | MRGPRX1 positive allosteric modulator |
| CAS | 1646499-97-9 |
| MW: | 360.4 D |
ab 149,00 €
