Zu "1646321-63-2" wurden 2 Artikel gefunden!
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Iptacopan hydrochloride
Artikelnummer: TGM-T9189-100mg
Description: Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Target: Complement System. Smiles:...
| Schlagworte: | Iptacopan HCl, LNP023 hydrochloride |
| Anwendung: | CFB inhibitor |
| CAS | 1646321-63-2 |
| MW: | 458.98 D |
ab 154,00 €
LNP023 (hydrochloride)
Artikelnummer: Cay37291-1
LNP023 is a complement factor B (CFB) inhibitor (IC50 = 10 nM). It is selective for CFB over a panel of 41 proteases and 110 other enzymes, receptors, and ion channels (IC50s = >30 µM for all). LNP023 inhibits formation of the membrane attack complex induced by zymosan A (Cay-21175) in isolated human whole blood...
| Schlagworte: | Ipatacopan, 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]-2-piperidinyl]-benzoic acid, monohydrochloride |
| Anwendung: | CFB inhibitor |
| CAS | 1646321-63-2 |
| MW: | 459 D |
ab 111,00 €
