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ARN14974
Artikelnummer: TGM-T21658-100mg
Description: ARN14974 is a benzoxazolone carboxamide. ARN14974 is a potent inhibitor of acid ceramidase with IC50 of 79 nM[1]. Target: Others. Smiles: Fc1ccc(cc1)-c1ccc2n(C(=O)NCCCCc3ccccc3)c(=O)oc2c1. References: Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D....
| CAS | 1644158-57-5 |
| MW: | 404.43 D |
ab 40,00 €
ARN14974
Artikelnummer: Cay17119-1
ARN14974 is a benzoxazolone carboxamide inhibitor of acid ceramidase (IC50 = 79 nM). It inhibits acid ceramidase activity, reduces levels of sphingosine and dihydroceramide, and increases levels of ceramide in SW403 adenocarcinoma cells and RAW 264.7 murine macrophages when used at concentrations ranging from 0.1 to...
| Schlagworte: | Acid Ceramidase Inhibitor 17a, 6-(4-fluorophenyl)-2-oxo-N-(4-phenylbutyl)-3(2H)-benzoxazolecarboxamide |
| Anwendung: | Acid ceramidase inhibitor |
| CAS | 1644158-57-5 |
| MW: | 404.4 D |
ab 36,00 €
