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SAfit2
SAfit2

Artikelnummer: Cay24366-500

SAfit2 is a potent inhibitor of FK506-binding protein 51 (FKBP51, Ki = 6 nM). It is highly selective for FKBP51 over FKBP52 (Ki = >50,000 nM) and has increased brain permeability in comparison to SAfit1. SAfit2 (20 mg/kg) enhances HPA axis suppression in mice by decreasing plasma corticosterone levels to a greater...
Schlagworte: (2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]-2-piperidinecarboxylic acid,...
Anwendung: FKBP5 inhibitor
CAS 1643125-33-0
MW: 803 D
ab 199,00 €
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SAFit2
SAFit2

Artikelnummer: TGM-T16836-100mg

Description: SAFit2 is a highly effective and selective fk506 binding protein 51(FKBP51) inhibitor (Ki: 6 nM). SAFit2 can enhance AKT2-AS160 binding and participate in the downstream response of glucocorticoid release in vivo, and is a candidate compound for the treatment of obesity, chronic pain, depression and...
Anwendung: FKBP5 inhibitor
CAS 1643125-33-0
MW: 802.99 D
ab 79,00 €
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