Zu "1642288-47-8" wurden 2 Artikel gefunden!
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Mavacamten
Artikelnummer: Cay19216-1
Mavacamten is an orally bioavailable inhibitor of cardiac myosin ATPase (IC50 = 0.3 µM in purified bovine myosin S1). It is selective for cardiac myosin over skeletal myosin (IC50 = 4.7 µM) and does not induce skeletal muscle impairments. It slows the rate of ATPase activity in both murine and bovine myofibrils,...
| Schlagworte: | SAR439152, 3-(1-methylethyl)-6-[[(1S)-1-phenylethyl]amino]-2,4(1H,3H)-pyrimidinedione |
| Anwendung: | Cardiac myosin ATPase inhibitor |
| CAS | 1642288-47-8 |
| MW: | 273.3 D |
ab 85,00 €
Mavacamten
Artikelnummer: TGM-T7134-100mg
Description: Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively). Target: Myosin. Smiles: CC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O. References: Kawas R F , Anderson R L , Ingle S R B , et al. A small molecule...
| Schlagworte: | MYK-461, SAR439152 |
| Anwendung: | Targets myosin heavy chain 6/7 (MYH6_7) |
| CAS | 1642288-47-8 |
| MW: | 273.33 D |
ab 42,00 €
