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Phosphoramidon (sodium salt)
Artikelnummer: Cay15113-1
Neprilysin (NEP) and NEP2 are membrane-bound zinc metalloproteases. Phosphoramidon is a natural and potent inhibitor of NEP and NEP2, with Ki values of 2 nM for both enzymes. It is also a weak inhibitor of the related zinc metalloprotease endothelin-converting enzyme (Ki = 3.5 µM). Phosphoramidon has little or no...
| Schlagworte: | N-[N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan, disodium salt |
| Anwendung: | NEP / NEP2 inhibitor |
| CAS | 164204-38-0 |
| MW: | 589.5 D |
ab 128,00 €
Phosphoramidon . disodium salt
Artikelnummer: AG-CP3-7008-M005
Phosphoramidon is a potent, reversible and competitive inhibitor of multiple soluble and membrane-bound zinc metalloproteases, particularly gluzincins, such as neutral endopeptidase NEP (Neprilysin, CD10, EC 3.4.24.11) (Ki = 2nM), NEP2 (Neprilysin-2) (Ki ~ 2nM), or endothelin-converting enzyme (ECE) (IC50 = 0.68µM)....
| Anwendung: | Potent, reversible, competitive zinc metalloproteases inhibitor |
| CAS | 164204-38-0 |
| MW: | 587.5 D |
ab 110,00 €
