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GS-9901
Artikelnummer: LKT-G720009.1
Selective inhibitor of the delta isoform of PI3K (PI3Kdelta).
| Schlagworte: | GS 9901, GS9901 |
| Anwendung: | Selective PI3Kdelta inhibitor |
| CAS | 1640247-87-5 |
| MW: | 477.89 D |
ab 123,00 €
GS-9901
Artikelnummer: TGM-T15420-100mg
Description: GS-9901 is a selective, orally active and potent PI3Kdelta inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Target: PI3K. Smiles: [C@@H](NC=1C(C#N)=C(N)N=C(N)N1)(C=2N(C(=O)C=3C(N2)=C(F)C=CC3Cl)C=4C=CC=NC4)C5CC5. References: Patel L, et al. Discovery of...
| Anwendung: | Selective PI3Kdelta inhibitor |
| CAS | 1640247-87-5 |
| MW: | 477.88 D |
ab 79,00 €
GS-9901
Artikelnummer: Cay42105-1
A PI3Kdelta inhibitor (IC50 = 1 nM), selective for PI3Kdelta over PI3Kalpha, PI3Kbeta, and PI3Kgamma (IC50s = 750, 100, and 190 nM, respectively) and a panel of 456 additional kinases, including 11 lipid and 56 mutant kinases, at 10 µM, activates basophils in isolated human whole blood (EC50 = 1 nM), decreases ankle...
| Schlagworte: | 2,4-diamino-6-[[(S)-[5-chloro-8-fluoro-3,4-dihydro-4-oxo-3-(3-pyridinyl)-2-quinazolinyl]cyclopropylmethyl]amino]-5-pyrimid... |
| Anwendung: | PI3Kdelta inhibitor |
| CAS | 1640247-87-5 |
| MW: | 477.9 D |
ab 122,00 €
