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BQU57
Artikelnummer: Cay16960-5
BQU57 is an inhibitor of the Ras-like GTPases RalA and RalB. It binds to RalB when RalB is bound to GDP with a Kd value of 7.7 µM, as determined by isothermal titration calorimetry (ITC). BQU57 (10 µM) decreases RalA and RalB activity in H2122 and H358 cells. It also inhibits colony formation of Ral-dependent H2122...
| Schlagworte: | 6-amino-1,4-dihydro-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-pyrano[2,3-c]pyrazole-5-carbonitrile |
| Anwendung: | RalA / RalB inhibitor |
| CAS | 1637739-82-2 |
| MW: | 334.3 D |
ab 50,00 €
BQU57
Artikelnummer: TGM-T2267-100mg
Description: BQU57 selectively inhibits Ral over Ras or Rho and suppresses xenograft tumor growth. Target: GTPase, Ras. Smiles: Cc1nn(C)c2OC(N)=C(C#N)C(c12)c1ccc(cc1)C(F)(F)F
| Anwendung: | RalA / RalB inhibitor |
| CAS | 1637739-82-2 |
| MW: | 334.3 D |
ab 33,00 €
