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MAZ51
Artikelnummer: Cay16168-1
The VEGF receptors (VEGFRs) mediate signaling leading to angiogenesis, with VEGFR3 (FLT4), activated by VEGF isoforms VEGFC and VEGFD, primarily expressed on lymphatic endothelial cells and directing lymphangiogenesis. MAZ51 is an indolinone that selectively antagonizes the activation of VEGFR3 by VEGFC (IC50 = 1...
| Schlagworte: | 3-[[4-(dimethylamino)-1-naphthalenyl]methylene]-1,3-dihydro-2H-indol-2-one |
| Anwendung: | VEGFR-3 VEGF-C antagonist |
| CAS | 163655-37-6 |
| MW: | 314.4 D |
ab 73,00 €
MAZ51
Artikelnummer: TGM-T8496-100mg
Description: MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. Target: VEGFR, Apoptosis. Smiles: CN(C)c1ccc(\C=C2\C(=O)Nc3ccccc23)c2ccccc12. References: Kirkin V, et al. MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. Int J Cancer. 2004 Dec...
| Anwendung: | VEGFR-3 VEGF-C antagonist |
| CAS | 163655-37-6 |
| MW: | 314.38 D |
ab 33,00 €
