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Vimseltinib
Artikelnummer: TGM-T10652-100mg
Description: Vimseltinib (DCC-3014) is a dual inhibitor targeting c-FMS (CSF-IR) and c-Kit with IC50 values of less than 0.01 µM and 0.1-1 µM, respectively. Target: c-Kit, CSF-1R, c-Fms. Smiles: CC(C)Nc1ncc(-c2ccc(Oc3ccnc(c3)-c3cnn(C)c3)c(C)n2)c(=O)n1C. References: Yumi Ahn, et al. 2-aminopyrimidin-6-ones and...
| Schlagworte: | DCC-3014 |
| CAS | 1628606-05-2 |
| MW: | 431.49 D |
ab 83,00 €
Vimseltinib
Artikelnummer: Cay38783-10
Vimseltinib is an inhibitor of colony stimulating factor 1 receptor (CSF1R, IC50 = 3.7 nM). It is selective for CSF1R over FMS-related tyrosine kinase 3 (FLT3), PDGFRalpha, PDGFRbeta, and KIT (IC50s = >3,300, 436, 2,300, and 476 nM, respectively). Vimseltinib inhibits the proliferation of M-NFS-60 leukemia cells...
| Schlagworte: | DCC-3014,... |
| Anwendung: | CSF1R inhibitor |
| CAS | 1628606-05-2 |
| MW: | 431.5 D |
ab 63,00 €
