Zu "1627091-47-7" wurden 2 Artikel gefunden!
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MLi-2
Artikelnummer: TGM-T16115-100mg
Description: MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM),...
| Anwendung: | LRRK2 inhibitor |
| CAS | 1627091-47-7 |
| MW: | 379.46 D |
ab 60,00 €
MLi-2
Artikelnummer: Cay19305-1
MLi-2 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 0.76 nM). It is greater than 100-fold selective for LRRK2 over a panel of 308 protein kinases, as well as a panel of receptors and ion channels, at 10 µM. It increases glucocerebrosidase (GCase) activity in dopaminergic neurons differentiated from...
| Schlagworte: | rel-3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole |
| Anwendung: | LRRK2 inhibitor |
| CAS | 1627091-47-7 |
| MW: | 379.5 D |
ab 67,00 €
