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HQL-79
Artikelnummer: Cay10134-10
HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase. Structurally, it is a synthetic tetrazole compound originally prepared as a possible antihistamine. Subsequent evaluation in models of allergy and asthma demonstrates the HQL-79 is orally available, and inhibits the synthesis of PGD2...
| Schlagworte: | 4-(diphenylmethoxy)-1-[3-(1H-tetrazol-5-yl)propyl]-piperidine |
| Anwendung: | PGD synthase inhibitor |
| CAS | 162641-16-9 |
| MW: | 377.5 D |
ab 57,00 €
HQL-79
Artikelnummer: TGM-T15503-2mg
Description: HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 µM and IC50: 6 µM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS. Target: Others. Smiles:...
| Anwendung: | PGD synthase inhibitor |
| CAS | 162641-16-9 |
| MW: | 377.48 D |
ab 107,00 €
