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Chidamide
Artikelnummer: Cay13686-1
Chidamide is an inhibitor of histone deacetylases (HDACs, IC50s = 0.095, 0.160, 0.067, 0.733, 0.078, and 0.432 µM for HDAC1-3, 8, 10, and 11, respectively). It is selective for these HDACs over HDAC4-7 and 9 (IC50s = >30 µM for all). Chidamide also inhibits nicotinamide phosphoribosyltransferase (Nampt, IC50 = 2.1...
| Schlagworte: | CS 055, HBI 8000, Tucidinostat, N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide |
| Anwendung: | HDAC inhibitor |
| CAS | 1616493-44-7 |
| MW: | 390.4 D |
ab 56,00 €
Tucidinostat
Artikelnummer: TGM-T4481-100mg
Description: Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9. Target: HDAC. Smiles:...
| Schlagworte: | Chidamide, CS 055, HBI-8000 |
| Anwendung: | Targets natural killer cell receptor 2B4 (CD244) |
| CAS | 1616493-44-7 |
| MW: | 390.41 D |
ab 55,00 €
