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UCB 9608
Artikelnummer: Cay43027-10
UCB 9608 is an inhibitor of PI4KIIIbeta (IC50 = 11 nM). It is selective for PI4KIIIbeta over 8 other phosphatidylinositol kinases at 10 µM. UCB 9608 inhibits the mixed lymphocyte reaction in isolated human peripheral blood mononuclear cells (PBMCs, IC50 = 37 nM). It increases heart allograft survival in mice when...
| Schlagworte: | (3S)-4-(6-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methyl-1-piperazinecarboxamide |
| Anwendung: | PI4KIII beta (PI4KB, phosphatidylinositol 4-kinase B) inhibitor |
| CAS | 1616413-96-7 |
| MW: | 410.48 D |
ab 60,00 €
UCB9608
Artikelnummer: TGM-TQ0009-100mg
Description: UCB9608 is a selective and orally active PI4KIIIbeta inhibitor (IC50: 11 nM), selective over PI3KC2 alpha, beta, and gamma lipid kinases. Target: PI4K. Smiles: COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)ncc23)c(C)c1. References: Reuberson J, et al. Discovery of a Potent, Orally Bioavailable...
| CAS | 1616413-96-7 |
| MW: | 410.47 D |
ab 48,00 €
