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DprE1-IN-2
Artikelnummer: TGM-T4044-10mg
Description: DprE1-IN-2 is an effective DprE1 inhibitor. Target: Antibacterial, DprE1. Smiles: CN(C)c1ncnc(Cn2cc(C(=O)NCCO)c3ncc(C)cc23)c1C. References: Shirude PS et al. Lead optimization of 1,4-azaindoles as antimycobacterial agents. J Med Chem. 2014 Jul 10,57(13):5728-37.
| Anwendung: | DprE1 inhibitor |
| CAS | 1615713-87-5 |
| MW: | 368.43 D |
ab 42,00 €
DprE1-IN-2
Artikelnummer: Cay21034-1
DprE1-IN-2 is an antitubercular agent that is active against M. tuberculosis in vitro, with MIC values ranging from 0.5 to 1.56 µM. It is an inhibitor of decaprenylphosphoryl-beta-D-ribose 2'-epimerase (DprE1, IC50 = 32 nM), an enzyme involved in mycobacterial cell wall biogenesis. DrpE1-IN-2 (300 mg/kg) reduces...
| Schlagworte: | 1-[[6-(dimethylamino)-5-methyl-4-pyrimidinyl]methyl]-N-(2-hydroxyethyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide |
| Anwendung: | DprE1 inhibitor |
| CAS | 1615713-87-5 |
| MW: | 368.4 D |
ab 52,00 €
