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SGC-CBP30
Artikelnummer: TGM-T6668-100mg
Description: SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM). Target: Histone Acetyltransferase, Epigenetic Reader Domain. Smiles: COc1ccc(CCc2nc3cc(ccc3n2C[C@H](C)N2CCOCC2)-c2c(C)noc2C)cc1Cl. References: Structural Genomics Consortium
| Anwendung: | CREBBP / EP300 bromodomain inhibitor |
| CAS | 1613695-14-9 |
| MW: | 509.04 D |
ab 45,00 €
SGC-CBP30
Artikelnummer: Cay14469-5
cAMP-responsive element-binding protein binding protein (CREBBP) and E1A-associated protein p300 (EP300) are transcriptional co-activators. Each contains a bromodomain, which recognizes acetylated lysine residues on target proteins. SGC-CBP30 is a potent inhibitor of CREBBP and EP300 bromodomains (IC50s = 21-69 and...
| Schlagworte: | 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-4-isoxazolyl)-1-[(2S)-2-(4-morpholinyl)propyl]-1H-benzimidazole |
| Anwendung: | CREBBP / EP300 bromodomain inhibitor |
| CAS | 1613695-14-9 |
| MW: | 509 D |
ab 150,00 €
