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Mps1-IN-3
Artikelnummer: Cay41029-10
Mps1-IN-3 is an inhibitor of monopolar spindle 1 (Mps1, IC50 = 50 nM). It inhibits the proliferation of U251 glioblastoma cells (IC50 = ~5 µM). Mps1-IN-3 (2 µM) prevents checkpoint-mediated mitotic arrest induced by nocodazole (Cay-13857) in U2OS osteosarcoma cells and, when used at a concentration of 5 µM in...
| Schlagworte: | Monopolar Spindle 1 Inhibitor 3, Monopolar Spindle1-IN-3, Mps1 Inhibitor 3,... |
| Anwendung: | Serine/threonine-protein kinase TTK/MPS1 inhibitor |
| CAS | 1609584-72-6 |
| MW: | 537.6 D |
ab 91,00 €
NEU
Mps1-IN-3
Artikelnummer: TGM-T16130-100mg
Description: Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM). Target: Kinesin. Smiles: COc1cc(ccc1Nc1nc(Nc2ccccc2S(=O)(=O)C(C)C)c2nc[nH]c2n1)N1CCC(O)CC1. References: Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J...
| Anwendung: | Serine/threonine-protein kinase TTK/MPS1 inhibitor |
| CAS | 1609584-72-6 |
| MW: | 537.63 D |
ab 30,00 €
