Zu "1603845-32-4" wurden 2 Artikel gefunden!
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TX1-85-1
Artikelnummer: TGM-T17182-10mg
Description: TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. Target: EGFR. Smiles:...
| Anwendung: | ErbB3 inhibitor |
| CAS | 1603845-32-4 |
| MW: | 580.68 D |
ab 63,00 €
TX1-85-1
Artikelnummer: Cay19164-1
TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It also binds to ErbB2, Lyn, and several other Src family kinases in a live cell chemical proteomics assay when used at a concentration of 2 µM. TX1-85-1 inhibits phosphorylation of Akt and ERK1/2 in...
| Schlagworte: | N-[5-[1-[4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-phenoxyphenyl]-2-propenamide |
| Anwendung: | ErbB3 inhibitor |
| CAS | 1603845-32-4 |
| MW: | 580.7 D |
ab 145,00 €
