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Deruxtecan
Artikelnummer: Cay43189-10
A reactive drug-linker molecule containing Dxd, has been linked trastuzumab as an ADC to target Dxd to tumor cells, binds to HER2 in a cell-free assay, is cytotoxic to breast cancer cells in vitro, and induces tumor regression in a BT474 breast cancer mouse xenograft model. when linked to trastuzumab. Formulation: A...
| Schlagworte: | Maleimidocaproyl-Gly-Gly-Phe-Gly-Dxd, Mc-GGFG-Dxd,... |
| Anwendung: | Reactive drug-linker molecule, ADC |
| CAS | 1599440-13-7 |
| MW: | 1034.07 D |
ab 73,00 €
Deruxtecan
Artikelnummer: TGM-T15098-10mg
Description: Deruxtecan is an ADC drug-linker conjugate comprising a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used in synthesizing DS-8201 and U3-1402. Target: Others, Drug-Linker Conjugates for ADC. Smiles:...
| CAS | 1599440-13-7 |
| MW: | 1034.05 D |
ab 131,00 €
