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Val-Cit-PAB-OH
Val-Cit-PAB-OH

Artikelnummer: Cay34818-100

Val-Cit-PAB-OH is a peptide linker molecule used in the synthesis of drug conjugates. It is cleaved by cathepsin B, a protease highly expressed in cancer cells, which confers specificity of the drug conjugates to cancer cells. Val-Cit-PAB-OH has been used in the synthesis of antibody-drug conjugates (ADCs)...
Schlagworte: Valine-Citrulline-p-Aminobenzylcarbamate, VC-PAB, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
Anwendung: Peptide linker molecule, cathepsin B substrate
CAS 159857-79-1
MW: 379.5 D
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Val-Cit-PAB-OH
Val-Cit-PAB-OH

Artikelnummer: CSB-DT2574.1

Amino acids are the basic units of proteins, which are linked by peptide bonds to form polypeptide chains that fold into proteins with specific functions. There are 20 common standard amino acids in nature, primarily distinguished by their side chains (R-groups). These differences give amino acids different...
CAS 159857-79-1
MW: 379.461 D
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