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Melagatran
Melagatran

Artikelnummer: Cay9002300-1

Melagatran is an inhibitor of thrombin (Ki = 0. µM) and an active metabolite of the prodrug ximelagatran (Cay-16862). It is selective for thrombin over a variety of serine proteases (Kis = 0.6-10. µM) but also inhibits trypsin (Ki = 0. µM). Melagatran inhibits thrombin-induced aggregation of isolated washed human...
Schlagworte: N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]-glycine
Anwendung: Thrombin inhibitor, ximelagatran metabolite
CAS 159776-70-2
MW: 429.51 D
557,00 €
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Melagatran
Melagatran

Artikelnummer: TGM-T11994-100mg

Description: Melagatran, a direct and orally active thrombin inhibitor, specifically inhibits thrombin without affecting other enzymes in the coagulation cascade or fibrinolytic enzymes. It does not rely on endogenous co-factors to exert its antithrombin effect, and may alleviate the harmful effects of endotoxemia....
Anwendung: Targets coagulation factor II (thrombin) [EC:3.4.21.5] (F2)
CAS 159776-70-2
MW: 429.51 D
ab 511,00 €
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