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JPH203 dihydrochloride
Artikelnummer: TGM-T11727-100mg
Description: JPH203 dihydrochloride (KYT-0353 dihydrochloride) is a tyrosine analog, acts as a selective inhibitor of L-type amino acid transporter 1 (LAT1), and is used in cancer research. Target: Others. Smiles: C1=CC=C(C=C1)C2=NC3=CC(=CC(=C3O2)COC4=C(C=C(C=C4Cl)C[C@@H](C(=O)O)N)Cl)N.Cl.Cl. References: Oda K, et...
| Schlagworte: | KYT-0353 dihydrochloride |
| CAS | 1597402-27-1 |
| MW: | 545.24 D |
ab 103,00 €
JPH203 (hydrochloride)
Artikelnummer: Cay36053-5
JPH203 is an inhibitor of L-type amino acid transporter 1 (LAT1, IC50 = 0.14 µM for 14C-leucine uptake in S2 cells expressing the human transporter). It is selective for LAT1 over LAT2 (IC50 = >10 µM). JPH203 inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 µM, respectively). It...
| Schlagworte: | KYT-0353, O-[(5-amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine, dihydrochloride |
| Anwendung: | LAT1 (L-type amino acid transporter, SLC7A5) inhibitor |
| CAS | 1597402-27-1 |
| MW: | 545.2 D |
ab 85,00 €
