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IT-901
IT-901

Artikelnummer: TGM-T15601-100mg

Description: IT-901 is an orally active and potent NF-kappaB subunit c-Rel inhibitor with IC50 values for NF-kappaB and c-Rel binding to DNA of 0.1 µM and 3 µM, respectively. IT-901 is a naphthalene thiobarbiturate derivative with antitumor activity and is used for the prevention and treatment of human lymphoma and...
Anwendung: c-Rel inhibitor
CAS 1584121-99-2
MW: 342.37 D
ab 120,00 €
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IT-901
IT-901

Artikelnummer: Cay22298-1

IT-901 is an inhibitor of the NF-kappaB subunit c-Rel. It inhibits NF-kappaB DNA binding in HBL1 cells (IC50 = 0.1 µM) and reduces TNF-alpha-induced NF-kappaB activity in a reporter assay (IC50 = 4 µM). IT-901 decreases proliferation of activated B-like (ABC) and germinal center B-like (GCB) human diffuse large B...
Schlagworte: 5-[(2,4-dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
Anwendung: c-Rel inhibitor
CAS 1584121-99-2
MW: 342.4 D
ab 44,00 €
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