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VUF 10166
VUF 10166

Artikelnummer: Cay31423-10

VUF 10166 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3A (Ki = 0.04 nM). It is selective for 5-HT3A over 5-HT3AB receptors in radioligand binding assays (Ki = 2 nM), as well as alpha7 nicotinic acetylcholine receptors (nAChRs) at 100 µM. VUF 10166 also acts as a partial agonist at 5-HT3A receptors...
Schlagworte: 2-chloro-3-(4-methyl-1-piperazinyl)-quinoxaline
Anwendung: 5-HT3 receptor antagonist
CAS 155584-74-0
MW: 262.7 D
ab 122,00 €
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VUF 10166
VUF 10166

Artikelnummer: TGM-T6728-100mg

Description: VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower. Target: 5-HT Receptor. Smiles: CN1CCN(CC1)c1nc2ccccc2nc1Cl. References: Thompson AJ, et al. J Pharmacol Exp Ther, 2012, 341(2), 350-9.
Anwendung: 5-HT3 receptor antagonist
CAS 155584-74-0
MW: 262.74 D
ab 30,00 €
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