Zu "1542213-00-2" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NCT-502
Artikelnummer: TGM-T16277-100mg
Description: NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 µM against PHGDH. Target:...
| Schlagworte: | N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide |
| Anwendung: | PHGDH inhibitor |
| CAS | 1542213-00-2 |
| MW: | 395.45 D |
ab 34,00 €
NCT-502
Artikelnummer: Cay19716-1
NCT-502 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 3.7 µM. It is inactive against a panel of other dehydrogenases and shows minimal cross reactivity with G protein-coupled receptors. NCT-502 reversibly blocks the...
| Schlagworte: | N-(4,6-dimethyl-2-pyridinyl)-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarbothioamide |
| Anwendung: | PHGDH inhibitor |
| CAS | 1542213-00-2 |
| MW: | 395.4 D |
ab 44,00 €
