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Pemigatinib
Artikelnummer: Cay33260-5
Pemigatinib is an inhibitor of FGFR (IC50s = 0.4, 0.5, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It is selective for FGFR1, FGFR2, and FGFR3 over FGFR4 and the kinase insert domain receptor (KDR, IC50s = 30 and 70 nM, respectively), as well as over a panel of 56 tyrosine and serine/threonine kinases at 10...
| Schlagworte: | INCB054828,... |
| Anwendung: | FGFR inhibitor |
| CAS | 1513857-77-6 |
| MW: | 487.5 D |
ab 72,00 €
Pemigatinib
Artikelnummer: TGM-T12401-100mg
Description: Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR, with IC50 values of 0.4 nM for FGFR1, 0.5 nM for FGFR2, 1.2 nM for FGFR3, and 30 nM for FGFR4. Target: FGFR. Smiles: CCN1C(=O)N(Cc2c[nH]c3nc(CN4CCOCC4)cc3c12)c1c(F)c(OC)cc(OC)c1F. References: Arudra K, et al. Calcinosis cutis...
| Schlagworte: | INCB054828 |
| Anwendung: | Targets fibroblast growth factor receptor 2 [EC:2.7.10.1] (FGFR2, CD332) |
| CAS | 1513857-77-6 |
| MW: | 487.5 D |
ab 39,00 €
