Zu "149647-78-9" wurden 4 Artikel gefunden!
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SAHA
Artikelnummer: Cay10009929-100
SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.Formal Name:...
| Schlagworte: | Suberoylanilide Hydroxamic Acid, Vorinostat, N1-hydroxy-N8-phenyl-octanediamide |
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264.3 D |
ab 34,00 €
Vorinostat
Artikelnummer: LKT-V5734.100
Vorinostat is a histone deacetylase inhibitor and has a broad spectrum of epigenetic activities. It is used in the treatment of cutaneous T cell lymphoma. It has also been shown to have both in vitro and in vivo effects against latently HIV infected T cells.
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264,32 D |
ab 129,00 €
Vorinostat (MK-0683, SAHA, Suberoylanilide Hydroxamic...
Artikelnummer: LC-V-8477_250mg
Soluble in DMSO at 66 mg/mL, soluble in ethanol at 2 mg/mL with slight warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 20-50 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | Suberoylanilide Hydroxamic Acid, Vorinostat, N1-hydroxy-N8-phenyl-octanediamide |
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264,32 D |
ab 85,00 €
Vorinostat
Artikelnummer: SYN-3006-M005
Solid. Soluble in DMSO or ethanol. Almost insoluble in water. Vorinostat (SAHA, MK0683, Zolinza) inhibits the enzymatic activity of histone deacetylases HDAC1, HDAC2 and HDAC3 (Class I) and HDAC6 (Class II) at nanomolar concentrations (IC50< 86 nM). These enzymes catalyze the removal of acetyl groups from the lysine...
| Schlagworte: | SAHA, MK0683, Zolinza |
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264,3 D |
ab 53,00 €
