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UNC2881
Artikelnummer: Cay29012-5
UNC2881 is an inhibitor of Mer (IC50 = 4.3 nM), a member of the TAM family of receptor tyrosine kinases. It is selective for Mer over the remaining TAM family members Axl and TYRO3 (IC50s = 360 and 250 nM, respectively). UNC2881 inhibits phosphorylation of Mer in 697 B-ALL acute lymphoblastic leukemia cells (IC50 =...
| Schlagworte: | 2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide |
| Anwendung: | Mer inhibitor |
| CAS | 1493764-08-1 |
| MW: | 463.6 D |
ab 164,00 €
UNC2881
Artikelnummer: TGM-T2629-100mg
Description: UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively. Target: TAM Receptor, Influenza Virus. Smiles: CCCCNc1ncc(C(=O)NCc2ccc(cc2)-n2ccnc2)c(NC2CCC(O)CC2)n1
| Anwendung: | Mer inhibitor |
| CAS | 1493764-08-1 |
| MW: | 463.58 D |
ab 38,00 €
