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Adomeglivant
Artikelnummer: Cay29668-5
Adomeglivant is an allosteric antagonist of the glucagon receptor. It inhibits glucagon-induced increases in cAMP levels in HEK293 cells expressing the rat glucagon or GLP-1 receptors (IC50s = 1.8 and 1.2 µM, respectively) but has no effect on cAMP levels when used alone. Adomeglivant also inhibits increases in cAMP...
| Schlagworte: | LY2409021,... |
| Anwendung: | Allosteric glucagon receptor antagonist |
| CAS | 1488363-78-5 |
| MW: | 555.6 D |
ab 51,00 €
NEU
Adomeglivant
Artikelnummer: TGM-T14130-100mg
Description: Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus. Target: Glucagon Receptor. Smiles: Cc1cc(O[C@@H](CCC(F)(F)F)c2ccc(cc2)C(=O)NCCC(O)=O)cc(C)c1-c1ccc(cc1)C(C)(C)C. References: Li Y et al. Efficient Synthesis of...
| Schlagworte: | LY2409021 |
| Anwendung: | Antidiabetic |
| CAS | 1488363-78-5 |
| MW: | 555.63 D |
ab 73,00 €
