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L-161,982
L-161,982

Artikelnummer: Cay10011565-1

Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
Schlagworte: N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony...
Anwendung: EP4 receptor antagonist
CAS 147776-06-5
MW: 654.7 D
ab 52,00 €
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L-161982
L-161982

Artikelnummer: TGM-T15681-100mg

Description: L-161982 is a selective antagonist of EP4 receptor. L-161982 could inhibit PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 could alleviate collagen-induced arthritis in mice. Target: Prostaglandin Receptor. Smiles:...
Anwendung: EP4 receptor antagonist
CAS 147776-06-5
MW: 654.72 D
ab 72,00 €
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