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Rosuvastatin (sodium salt)
Artikelnummer: Cay44550-100
Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the...
| Schlagworte: | ZD 4522,... |
| Anwendung: | HMG-CoA reductase inhibitor |
| CAS | 147098-18-8 |
| MW: | 503,52 D |
ab 73,00 €
Rosuvastatin Sodium
Artikelnummer: TGM-T63430-10mg
Description: Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50: 11 nM) that effectively blocks hERG currents (IC50: 195 nM), reduces the expression of mature hERG, and inhibits the interaction of heat shock protein 70 (Hsp70) with hERG protein. Target: Others. Smiles:...
| CAS | 147098-18-8 |
| MW: | 503.52 D |
ab 30,00 €
