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Meclinertant
Artikelnummer: TGM-T16034-100mg
Description: Meclinertant (SR 48692) is a neurotensin receptor-1 (NT1) antagonist that blocks neurotensin-induced excitation and can be used to study neurological disorders. Target: Neurotensin Receptor. Smiles: O=C(O)C1(NC(=O)C2=NN(C=3C=CN=C4C=C(Cl)C=CC43)C(=C2)C=5C(OC)=CC=CC5OC)C6CC7CC(C6)CC1C7. References: Jolas...
| Schlagworte: | SR 48692 |
| Anwendung: | NTSR1 antagonist |
| CAS | 146362-70-1 |
| MW: | 587.07 D |
ab 77,00 €
SR 48692
Artikelnummer: Cay20124-1
SR 48692 is an orally bioavailable allosteric antagonist of the neurotensin receptor NTS1 (Kd = 3.4 nM). SR 48692 inhibits high affinity neurotensin binding to brain tissue from guinea pig, newborn mouse, newborn human, and adult human as well as rat mesencephalic cells and HT-29 cells with IC50 values ranging from...
| Schlagworte: | 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carbox... |
| Anwendung: | NTSR1 antagonist |
| CAS | 146362-70-1 |
| MW: | 587.1 D |
ab 44,00 €
