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SR-3029
Artikelnummer: TGM-T3972-10mg
Description: SR-3029 is a highly potent and specific inhibitor of CK1delta/CK1epsilon. Target: Casein Kinase. Smiles: Fc1cccc(c1)-n1cnc2c(NCc3nc4ccc(F)c(F)c4[nH]3)nc(nc12)N1CCOCC1. References: Rosenberg LH,et al. Therapeutic targeting of casein kinase 1delta in breast cancer. Sci Transl Med. 2015 Dec...
| Schlagworte: | SR3029 |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 1454585-06-8 |
| MW: | 480.45 D |
ab 31,00 €
SR 3029
Artikelnummer: Cay27048-5
SR 3029 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 44 and 260 nM, respectively). It is selective for CK1delta and CK1epsilon over 438 kinases in a panel but also inhibits MYLK4, FLT3, Cdk4/cyclin D1, and MARK2 by greater than 90% at 10 µM. SR 3029 inhibits Cdk4/cyclin D1, Cdk4/cyclin...
| Schlagworte: | N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 1454585-06-8 |
| MW: | 480.5 D |
ab 117,00 €
