Zu "1453848-26-4" wurden 3 Artikel gefunden!
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Ravoxertinib
Artikelnummer: TGM-T6511-100mg
Description: Ravoxertinib (GDC-0994) is an efficacious, orally available ERK1/2 inhibitor with an IC50 of 1.1/0.3 nM. Target: ERK. Smiles: Cn1nccc1Nc1nccc(n1)-c1ccn([C@H](CO)c2ccc(Cl)c(F)c2)c(=O)c1. References: AACR2014. Abstract.
| Schlagworte: | GDC-0994 |
| Anwendung: | Targets mitogen-activated protein kinase 1/3 [EC:2.7.11.24] (ERK, MAPK1_3) |
| CAS | 1453848-26-4 |
| MW: | 440.86 D |
ab 34,00 €
GDC-0994
Artikelnummer: Cay21107-1
GDC-0994 is a potent and selective ERK1 and ERK2 inhibitor with IC50 values of 6.1 and 4.1 nM, respectively. It inhibits ERK-dependent p90RSK serine 380 phosphorylation in PMA-stimulated HepG2 cells with an IC50 value of 12 nM. GDC-0994 inhibited growth of HCT116 human colorectal cancer xenograft tumors by 49%, 57%,...
| Schlagworte: | RG-7842,... |
| Anwendung: | ERK1 & ERK2 inhibitor |
| CAS | 1453848-26-4 |
| MW: | 440.9 D |
ab 44,00 €
GDC-0994
Artikelnummer: LKT-G124080.1
ERK1/2 inhibitor.
| Schlagworte: | GDC0994, RG7842, Ravoxertinib |
| Anwendung: | ERK1 & ERK2 inhibitor |
| CAS | 1453848-26-4 |
| MW: | 440.86 D |
ab 142,00 €
