Zu "1448428-05-4" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Selonsertib Hydrochloride
Artikelnummer: SYN-1229-M001
Solid. Soluble in DMSO or ethanol. LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
| Schlagworte: | LY-2784544 |
| Anwendung: | JAK2 inhibitor |
| CAS | 1448428-05-4 |
| MW: | 469,9 D |
ab 139,00 €
BIX02565
Artikelnummer: SYN-1228-M100
Solid. Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water. TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
| Schlagworte: | TAK632 |
| Anwendung: | pan-RAF inhibitor |
| CAS | 1448428-05-4 |
| MW: | 554,5 D |
ab 139,00 €
Selonsertib HCl
Artikelnummer: TGM-T70622-100mg
Description: Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby...
| Anwendung: | pan-RAF inhibitor |
| CAS | 1448428-05-4 |
| MW: | 481.96 D |
ab 1.867,00 €
