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Selonsertib
Artikelnummer: TGM-T3350-100mg
Description: Selonsertib (GS-4997) is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Target: ASK, Apoptosis, MAPK. Smiles: CC(C)n1cnnc1-c1cccc(NC(=O)c2cc(c(C)cc2F)-n2cnc(c2)C2CC2)n1. References: Lin JH,...
| Schlagworte: | GS-4997 |
| Anwendung: | Targets mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] (MAP3K5, ASK1) |
| CAS | 1448428-04-3 |
| MW: | 445.49 D |
ab 34,00 €
Selonsertib
Artikelnummer: Cay20972-1
Selonsertib is an inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50 = 5.01 nM). It decreases apoptosis and stellate cell activation in an in vitro 3D-human liver microtissue model of non-alcoholic steatohepatitis (NASH) induced by palmitic acid (Cay-10006627) when used at a concentration of 1 µM....
| Schlagworte: | GS-4977, GS-4997,... |
| Anwendung: | ASK1 inhibitor |
| CAS | 1448428-04-3 |
| MW: | 445.5 D |
ab 44,00 €
Selonsertib
Artikelnummer: SYN-1231-M001
Solid. Soluble in DMSO. Insoluble in water. Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an...
| Schlagworte: | GS-4997 (free base),... |
| Anwendung: | ASK1 inhibitor |
| CAS | 1448428-04-3 |
| MW: | 445,5 D |
ab 139,00 €
GS-4997
Artikelnummer: LKT-G720004.100
ASK1 inhibitor.
| Schlagworte: | GS 4997, GS4997, Selonsertib |
| Anwendung: | ASK1 inhibitor |
| CAS | 1448428-04-3 |
| MW: | 445.5 D |
ab 99,00 €
