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GSK2837808A
GSK2837808A

Artikelnummer: Cay20626-1

GSK2837808A is a potent inhibitor of lactate dehydrogenase (LDH) A and B (IC50s = 2.6 and 0.43 nM, for human recombinant LDHA and LDHB, respectively). It inhibits lactate production in Snu398 hepatocellular carcinoma cells in which LDHB expression is undetectable (EC50 = 400 nM). GSK2837808A (10 µM) reduces glucose...
Schlagworte: 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-benzoic acid
Anwendung: LDHA inhibitor
CAS 1445879-21-9
MW: 649.6 D
ab 60,00 €
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-10 %
GSK2837808A
GSK2837808A

Artikelnummer: AG-CR1-3685-M005

Potent and selective cell permeable inhibitor of lactate dehydrogenase A (LDHA) (IC50 values are 2.6 and 43 nM for LDHA and LDHB, respectively). Decreases glycolysis. Useful agent for immunometabolism research. Exhibits antitumoral activity. Inhibits lactate production in selected cancer cell lines. Reduces glucose...
Schlagworte: 3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
Anwendung: Potent, selective cell-permeable LDHA inhibitor
CAS 1445879-21-9
MW: 649.6 D
50,00 € ab 45,00 €
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