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ML-297
Artikelnummer: Cay14792-10
G protein-regulated inwardly rectifying potassium (GIRK1-4) channels are a family of Kir3.1-Kir3.4 ion channels that modulate cell excitability. The four different GIRK subunits are composed in different homo- and heterotetrameric combinations, which are expressed with regional specificity throughout the central...
| Schlagworte: | CID-56642816, VU0456810, N-(3,4-difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-urea |
| Anwendung: | GIRK1/2 activator |
| CAS | 1443246-62-5 |
| MW: | 328.3 D |
ab 73,00 €
ML 297
Artikelnummer: TGM-T4664-100mg
Description: ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters....
| Schlagworte: | ML297 |
| Anwendung: | GIRK1/2 activator |
| CAS | 1443246-62-5 |
| MW: | 328.32 D |
ab 41,00 €
