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Eleclazine free base
Artikelnummer: TGM-T71945-50mg
Description: Eleclazine, also known as GS-6615, is a selective late sodium current inhibitor. Eleclazine is potentially useful for treatment of coronary vasodilators, antiarrhythmics and vasodilators. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the...
| Anwendung: | Targets voltage-gated sodium channel type I alpha (SCN1A, NAV1.1) |
| CAS | 1443211-72-0 |
| MW: | 415.37 D |
ab 85,00 €
Eleclazine
Artikelnummer: Cay36227-10
Eleclazine is an inhibitor of the cardiac late sodium current (INa). It inhibits INa in HEK293 cells expressing the alpha subunit of the voltage-gated sodium channel (Nav) isoform Nav1.5 (IC50 = 0.88 µM). Eleclazine is selective for the cardiac late INa over a panel of 11 cardiac ion channels at 1 µM, as well as...
| Schlagworte: | Dihydrobenzoxazepinone, GS-6615,... |
| Anwendung: | Cardiac late INa inhibitor, antiarrhythmic, antiischemic, sodium channel blocker |
| CAS | 1443211-72-0 |
| MW: | 415.4 D |
ab 42,00 €
