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GYKI 53655 hydrochloride
Artikelnummer: TGM-T15456-1mg
Description: GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders. Target: GluR. Smiles: Cl.CNC(=O)N1N=C(c2ccc(N)cc2)c2cc3OCOc3cc2CC1C. References: Bleakman D, et al. Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate...
| Schlagworte: | LY300168 hydrochloride, GYKI53655 hydrochloride |
| Anwendung: | Allosteric AMPA receptor antagonist |
| CAS | 143692-48-2 |
| MW: | 388.85 D |
49,00 €
GYKI 53655
Artikelnummer: Cay39842-1
GYKI 53655 is an allosteric AMPA receptor antagonist. It inhibits AMPA- and kainite-induced inward currents in whole-cell patch-clamp assays using primary rat hippocampal neurons (IC50s = 1.1 and 1.5 µM, respectively). GYKI 53655 decreases tonic and clonic audiogenic seizure severity in mice (ED50s = 1.3 and 2...
| Schlagworte: | LY300168, 5-(4-aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide,... |
| Anwendung: | Allosteric AMPA receptor antagonist |
| CAS | 143692-48-2 |
| MW: | 388.9 D |
ab 55,00 €
