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666-15
Artikelnummer: Cay30780-10
666-15 is an inhibitor of gene transcription mediated by cAMP-response-element-binding protein (CREB, IC50 = 81 nM in a cell-based reporter assay). It inhibits the growth of A549, MCF-7, MDA-MB-231, and MDA-MB-468 cells (GI50s = 0.47, 0.31, 0.073, and 0.046 µM, respectively). 666-15 (10 mg/kg per day, five days per...
| Schlagworte: | Compound 3i,... |
| Anwendung: | CREB-mediated gene transcription inhibitor |
| CAS | 1433286-70-4 |
| MW: | 620.5 D |
ab 228,00 €
666-15
Artikelnummer: TGM-T5318-100mg
Description: 666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer. Target: Epigenetic Reader Domain. Smiles: Cl.NCCCOc1cc2ccccc2cc1C(=O)NCCOc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cc1O. References: Qin Y, et al. Interfering MSN-NONO complex-activated CREB...
| Schlagworte: | CREB inhibitor |
| Anwendung: | CREB-mediated gene transcription inhibitor |
| CAS | 1433286-70-4 |
| MW: | 620.52 D |
ab 49,00 €
