Zu "1431698-10-0" wurden 3 Artikel gefunden!
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OTSSP167 hydrochloride
Artikelnummer: TGM-T21559-100mg
Description: OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM). Target: MELK. Smiles: Cl.CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(nc12)-c1cc(Cl)c(O)c(Cl)c1)C(C)=O. References: Chung S, Suzuki H, Miyamoto T, et al. Development of an orally-administrative MELK-targeting inhibitor that suppresses...
| CAS | 1431698-10-0 |
| MW: | 523.88 D |
ab 34,00 €
OTSSP167 (hydrochloride)
Artikelnummer: Cay16873-1
Maternal embryonic leucine zipper kinase (MELK) is a serine/threonine kinase that regulates signaling central to cell cycling, stem cell renewal, apoptosis, and other cellular processes. MELK is overexpressed in some forms of cancer, particularly those with aggressive undifferentiated tumors. OTSSP167 is a potent...
| Schlagworte: | 1-(6-(3,5-dichloro-4-hydroxyphenyl)-4-(((1r,4r)-4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethan-1-o... |
| Anwendung: | MELK inhibitor |
| CAS | 1431698-10-0 |
| MW: | 523.9 D |
ab 85,00 €
OTSSP167 Hydrochloride
Artikelnummer: LKT-O783743.1
MELK inhibitor.
| Schlagworte: | OTS167 Hydrochloride, OTSSP167 (hydrochloride), OTSSP167 HCL |
| Anwendung: | MELK inhibitor |
| CAS | 1431698-10-0 |
| MW: | 523.88 D |
ab 123,00 €
