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CCT241533 hydrochloride
Artikelnummer: TGM-T10718L-100mg
Description: CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM, IC50: 3 nM). Target: Chk. Smiles: Cl.COc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O. References: Anderson VE, et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates...
| CAS | 1431697-96-9 |
| MW: | 478.95 D |
ab 67,00 €
CCT241533 (hydrochloride)
Artikelnummer: Cay19178-1
CCT241533 is a selective inhibitor of checkpoint kinase 2 (Chk2, IC50 = 3 nM). In human cancer cell lines, CCT241533 blocks Chk2 activity and potentiates the cytotoxicity of the PARP inhibitors, rucaparib, AG-1447, (Cay-15643) and olaparib (Cay-10621).Formal Name:...
| Schlagworte: | (3R,4S)-rel-4-[[2-(5-fluoro-2-hydroxyphenyl)-6,7-dimethoxy-4-quinazolinyl]amino]-alpha,alpha-dimethyl-3-pyrrolidinemethano... |
| Anwendung: | Chk2 inhibitor |
| CAS | 1431697-96-9 |
| MW: | 479 D |
ab 52,00 €
