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ML-298
Artikelnummer: Cay15349-1
ML-298 is an inhibitor of phospholipase D2 (PLD2, IC50 = 355 nM). It is selective for PLD2 over PLD1 (IC50 = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 µM without inducing cytotoxicity.Formal Name:...
| Schlagworte: | 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide |
| Anwendung: | PLD2 inhibitor |
| CAS | 1426916-02-0 |
| MW: | 432.4 D |
ab 62,00 €
ML-298
Artikelnummer: TGM-T8966-100mg
Description: ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM). Target: Phospholipase. Smiles: Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(F)c(F)c2)CC1. References: Brown K A . Development of dual PLD1/2 and PLD2 selective inhibitors from a common...
| Schlagworte: | CID53393915, ML298 |
| Anwendung: | PLD2 inhibitor |
| CAS | 1426916-02-0 |
| MW: | 432.44 D |
ab 33,00 €
