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Nerandomilast
Artikelnummer: Cay44975-10
Nerandomilast is an inhibitor of phosphodiesterase 4B (PDE4B. IC50 = 0. µM). It is selective for PDE4B over PDE4A, PDE4C, and PDE4D (IC50s = 0. 8. and 0. µM, respectively), PDE7A, PDE3A, PDE1C, and PDE9A (IC50s = 14, 120, 46, and >100 µM, respectively), and does not inhibit PDE2A, PDE5, or PDE6. Nerandomilast...
| Schlagworte: | BI-1015550,... |
| Anwendung: | PDE4B inhibitor |
| CAS | 1423719-30-5 |
| MW: | 448.97 D |
ab 91,00 €
BI 1015550
Artikelnummer: TGM-T72031-100mg
Description: Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM. BI 1015550 has potential applications in inflammation, allergic diseases, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD) with a good safety profile. Target: PDE. Smiles:...
| CAS | 1423719-30-5 |
| MW: | 448.97 D |
ab 56,00 €
