Zu "1423715-37-0" wurden 2 Artikel gefunden!
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SP-2577
Artikelnummer: Cay43468-10
An LSD1 inhibitor (IC50 = 13 nM), induces cell death in a panel of 12 ovarian cancer cell lines expressing mutant SWI/SNF (IC50s = 0.013-2.819 µM), increases secretion of IFN-gamma, IFN-beta, IL-1beta, IL-2, and IL-6 in COV434 cells, decreases the viability of primary NKT cells and T cells and reduces the...
| Schlagworte: | Seclidemstat, 3-[(4-methyl-1-piperazinyl)sulfonyl]-benzoic acid, (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide |
| Anwendung: | LSD1 inhibitor |
| CAS | 1423715-37-0 |
| MW: | 450.94 D |
ab 72,00 €
Seclidemstat
Artikelnummer: TGM-T4527-100mg
Description: Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM. Target: Histone Demethylase. Smiles: CN1CCN(CC1)S(=O)(=O)c1cccc(c1)C(=O)N\N=C(/C)c1cc(Cl)ccc1O. References: SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLAS EINHIBITOR S. WO/2017/004519 A1
| Schlagworte: | SP-2577 |
| Anwendung: | Targets KDM1A (AOF2, LSD1) |
| CAS | 1423715-37-0 |
| MW: | 450.94 D |
ab 39,00 €
