Zu "1420477-60-6" wurden 3 Artikel gefunden!
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Acalabrutinib
Artikelnummer: Cay19899-1
Acalabrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (BTK). It can dose-dependently inhibit B cell receptor signaling in primary chronic lymphocytic leukemia cells. In kinase-inhibition assays, acalabrutinib was more selective than ibrutinib (Cay-16274) for inhibiting BTK and did not inhibit EGFR,...
| Schlagworte: | ACP-196, 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-benzamide |
| Anwendung: | BTK inhibitor |
| CAS | 1420477-60-6 |
| MW: | 465.5 D |
ab 43,00 €
Acalabrutinib, Free Base
Artikelnummer: LC-A-7337_100mg
Soluble in DMSO. Acalabrutinib, also known as ACP-196, is an irreversible Bruton tyrosine kinase (BTK) inhibitor. It binds covalently to Cys481 with improved selectivity and in vivo target coverage. Acalabrutinib inhibited BTK with an IC50 of 3 nM and had improved target specificity over ibrutinib with 323-, 94-,...
| Schlagworte: | ACP196, ACP-196 |
| Anwendung: | Antineoplastic, Bruton's tyrosine kinase (BTK) inhibitor |
| CAS | 1420477-60-6 |
| MW: | 465.51 D |
ab 83,00 €
Acalabrutinib
Artikelnummer: LKT-A081014.100
| Schlagworte: | ACP-196 |
| Anwendung: | BTK inhibitor |
| CAS | 1420477-60-6 |
| MW: | 465.52 D |
ab 153,00 €
