Zu "1416334-69-4" wurden 2 Artikel gefunden!
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GSK-A1
Artikelnummer: SYN-1219-M001
Solid. Soluble in DMSO. GSK-A1 is a potent PI4KA inhibitor with an IC50 of about 3nM in vitro using HEK-AT1 cells. Phosphatidylinositol 4-kinase type III? (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory...
| Schlagworte: | 5-(2-Amino-1-(4-morpholinophenyl)-1H-benzo[d]imidazol-6-yl)-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide, GSKA1 |
| Anwendung: | Potent PI4KA inhibitor |
| CAS | 1416334-69-4 |
| MW: | 574,6 D |
ab 158,00 €
GSK-A1
Artikelnummer: Cay34502-1
GSK-A1 is an inhibitor of phosphatidylinositol 4-kinase IIIalpha (PI4KIIIalpha, IC50 = 3.16 nM). It is selective for PI4KIIIalpha over PI4KIIIbeta, PI3Kalpha, PI3Kbeta, and PI3Kdelta (IC50s = >50 nM) but also inhibits PI3Kgamma (IC50 = 15.8 nM). GSK-A1 decreases the levels of phosphatidylinositol 4-phosphate...
| Schlagworte: | 5-[2-amino-1-[4-(4-morpholinyl)phenyl]-1H-benzimidazol-6-yl]-N-(2-fluorophenyl)-2-methoxy-3-pyridinesulfonamide |
| Anwendung: | PI4KIIIalpha inhibitor |
| CAS | 1416334-69-4 |
| MW: | 574.6 D |
ab 40,00 €
