Zu "1414854-42-4" wurden 2 Artikel gefunden!
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Verosudil
Artikelnummer: Cay42234-10
A ROCK1 and ROCK2 inhibitor (Ki = 2 nM for both), selective for ROCK1 and ROCK2 over PKA, PKCtheta, MRCKalpha, and CaMKIV (Kis = 69, 9,332, 28, and 5,855 nM, respectively), decreases focal adhesion points on, and actin fiber length in, primary PTM cells at 1 µM, inhibits TGF-beta-induced increases in alpha-SMA...
| Schlagworte: | AR-12286, N-(1,2-dihydro-1-oxo-6-isoquinolinyl)-a-(dimethylamino)-3-thiopheneacetamide |
| Anwendung: | ROCK1 / ROCK2 inhibitor |
| CAS | 1414854-42-4 |
| MW: | 327.4 D |
ab 97,00 €
Verosudil
Artikelnummer: TGM-T60924-100mg
Description: Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 nM and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 mitigates steroid-induced intraocular pressure in mice by decreasing intraocular pressure through enhanced outflow of aqueous humor via the trabecular meshwork....
| Schlagworte: | AR-12286 |
| Anwendung: | Antiglaucoma, Rho-associated kinase inhibitor |
| CAS | 1414854-42-4 |
| MW: | 327.4 D |
ab 50,00 €
