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CAY10574
Artikelnummer: Cay10011247-5
Cyclin-dependent kinases (CDKs) play a key role in regulating cell division by phosphorylating distinct substrates in different phases of the cell cycle. Cell cycle deregulation in many cancers often results from altered CDK activity. Thus, CDKs are potential pharmacological targets for anticancer agents. CAY10574...
| Schlagworte: | 4-[(3,5-diamino-1H-pyrazol-4-yl)azo]-phenol |
| Anwendung: | CDK9 inhibitor |
| CAS | 140651-18-9 |
| MW: | 218.2 D |
ab 38,00 €
CAN508
Artikelnummer: TGM-T8796-100mg
Description: CAN508 is a potent ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 µM. It also competitively inhibits Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 µM and 20 µM, respectively. CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes....
| Anwendung: | CDK9 inhibitor |
| CAS | 140651-18-9 |
| MW: | 218.22 D |
ab 30,00 €
